Russo Eleonora, Potenza Domenico R, Casella Michela, Massaro Raimondo, Russo Giulio, Braccio Maurizio, Dello Russo Antonio, Cassese Mauro
Department of Cardiovascular Disease, Division of Cardiac Surgery, Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo, Italy.
Department of Cardiovascular Disease, Division of Cardiology, Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo, Italy.
Curr Cardiol Rev. 2019;15(3):205-218. doi: 10.2174/1573403X15666181205105821.
Transcather aortic valve implantation (TAVI) has become a safe and indispensable treatment option for patients with severe symptomatic aortic stenosis who are at high surgical risk. Recently, outcomes after TAVI have improved significantly and TAVI has emerged as a qualified alternative to surgical aortic valve replacement in the treatment of intermediate risk patients and greater adoption of this procedure is to be expected in a wider patients population, including younger patients and low surgical risk patients. However since the aortic valve has close spatial proximity to the conduction system, conduction anomalies are frequently observed in TAVI. In this article, we aim to review the key aspects of pathophysiology, current incidence, predictors and clinical association of conduction anomalies following TAVI.
经导管主动脉瓣植入术(TAVI)已成为手术风险高的重度症状性主动脉瓣狭窄患者安全且不可或缺的治疗选择。最近,TAVI术后的结果有了显著改善,并且在治疗中度风险患者方面,TAVI已成为外科主动脉瓣置换术的合格替代方案,预计在更广泛的患者群体中,包括年轻患者和低手术风险患者,该手术将得到更广泛的应用。然而,由于主动脉瓣与传导系统在空间上距离很近,TAVI中经常观察到传导异常。在本文中,我们旨在综述TAVI后传导异常的病理生理学关键方面、当前发生率、预测因素及临床关联。