Mo L Y, Bascom P A, Ritchie K, McCowan L M
Institute of Biomedical Engineering, University of Toronto, Canada.
Ultrasound Med Biol. 1988;14(5):365-76. doi: 10.1016/0301-5629(88)90072-5.
An electrical analogue model of an artery that terminates into a vascular bed is presented. The model consists of an uniform transmission line that represents the artery and a load impedance that represents the vascular bed. The transmission line parameters are based on a well-established first-order approximation of the Navier-Stokes equations for fluid flow in distensible tubes. The model can be used to predict the incident and reflected components of both the arterial pressure and flow waveforms. In addition, it can predict the vessel diameter change and the mean blood velocity waveforms. In this study, the model was applied to the uterine artery so that the characteristics of the utero-placental circulation can be related to Doppler ultrasound recordings. It was found that the presence of the dicrotic notch in the uterine artery time-velocity waveform is the result of wave reflection and that a persistent notch past 20 weeks' gestation may be indicative of an abnormally high placental bed resistance. It is shown that the simulation results are consistent with the known physiological data and the clinically recorded uterine Doppler waveforms.
提出了一种终止于血管床的动脉的电模拟模型。该模型由代表动脉的均匀传输线和代表血管床的负载阻抗组成。传输线参数基于用于可扩张管中流体流动的Navier-Stokes方程的成熟一阶近似。该模型可用于预测动脉压力和流量波形的入射和反射分量。此外,它还可以预测血管直径变化和平均血流速度波形。在本研究中,该模型应用于子宫动脉,以便将子宫-胎盘循环的特征与多普勒超声记录相关联。研究发现,子宫动脉时间-速度波形中重搏波切迹的出现是波反射的结果,妊娠20周后持续存在的切迹可能表明胎盘床阻力异常高。结果表明,模拟结果与已知的生理数据和临床记录的子宫多普勒波形一致。