Tian Yingying, Yang Xiuhua
Department of Obstetrics, The First Hospital of China Medical University, Shenyang, China.
Front Med (Lausanne). 2022 Mar 3;9:813343. doi: 10.3389/fmed.2022.813343. eCollection 2022.
The invasion of trophoblasts into the uterine decidua and decidual vessels is critical for the formation of placenta. The defects of placentation are related to the etiologies of preeclampsia (PE), fetal growth restriction (FGR), and small-for-gestational age (SGA) neonates. It is possible to predict significant vascular events during pregnancy through uterine artery Doppler (UAD). From the implantation stage to the end of pregnancy, detecting changes in uterine and placental blood vessels can provide a favorable diagnostic instrument for pregnancy complications. This review aims to collect literature about the roles of UAD in pregnancy complications. We consider all relevant articles in English from January 1, 1983 to October 30, 2021. Predicting pregnancy complications in advance allows practitioners to carry out timely interventions to avoid or lessen the harm to mothers and neonates. Administering low-dose aspirin daily before 16 weeks of pregnancy can significantly reduce the incidence of pregnancy complications. From early pregnancy to late pregnancy, UAD can combine with other maternal factors, biochemical indicators, and fetal measurement data to identify high-risk population. The identification of high-risk groups can also lessen maternal mortality. Besides, through moderate risk stratification, stringent monitoring for high-risk pregnant women can be implemented, decreasing the incidence of adversities.
滋养层细胞侵入子宫蜕膜和蜕膜血管对于胎盘形成至关重要。胎盘形成缺陷与子痫前期（PE）、胎儿生长受限（FGR）和小于胎龄（SGA）新生儿的病因有关。通过子宫动脉多普勒（UAD）预测孕期的重大血管事件是有可能的。从着床期到孕期结束，检测子宫和胎盘血管的变化可为妊娠并发症提供良好的诊断手段。本综述旨在收集有关UAD在妊娠并发症中作用的文献。我们纳入了1983年1月1日至2021年10月30日期间所有相关的英文文章。提前预测妊娠并发症可使从业者及时进行干预，以避免或减轻对母亲和新生儿的伤害。在妊娠16周前每日服用低剂量阿司匹林可显著降低妊娠并发症的发生率。从早孕到晚孕，UAD可与其他母体因素、生化指标和胎儿测量数据相结合，以识别高危人群。识别高危人群也可降低孕产妇死亡率。此外，通过适度的风险分层，可对高危孕妇实施严格监测，降低不良事件的发生率。
