Departments of Ophthalmology and Pediatrics, Emory University, Atlanta, Georgia, USA.
Curr Opin Neurol. 2019 Feb;32(1):75-81. doi: 10.1097/WCO.0000000000000644.
To review the recent advances in understanding how primary brain tumors affect vision in children.
Children with primary brain tumors may have vision loss due to involvement of their afferent visual pathways or from papilledema. These vision deficits may go unrecognized until later in life, years after treatment of the primary lesion. Strabismus and cranial nerve palsies may occur as a result of brain tumors. Ophthalmologists can monitor and treat young children at risk for vision loss from amblyopia as a result of effects from their underlying lesion. Advances in imaging techniques have made it possible to quantify damage to the visual pathways with objective tests.
Systematic referrals for evaluation by an ophthalmologist should occur early in the course of treatment of primary brain tumors as these evaluations may improve visual outcomes and quality of life.
了解儿童原发性脑肿瘤如何影响视力的最新进展。
儿童原发性脑肿瘤可能因视路受累或视乳头水肿而导致视力丧失。这些视力缺陷可能在治疗原发性病变多年后，直到生命后期才被发现。斜视和颅神经麻痹可能是脑肿瘤的结果。眼科医生可以监测和治疗因潜在病变而有弱视导致视力丧失风险的幼儿。成像技术的进步使得使用客观测试来量化视路损伤成为可能。
原发性脑肿瘤治疗过程中应尽早进行眼科评估，因为这些评估可能会改善视力结果和生活质量。
