原发性皮肤 γδT 细胞淋巴瘤小病灶经培拉曲塞治疗获得成功。

Small Primary Cutaneous γδT-Cell Lymphoma Lesions Successfully Treated With Pralatrexate.

机构信息

From the Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan.

出版信息

Clin Nucl Med. 2019 Feb;44(2):e85-e86. doi: 10.1097/RLU.0000000000002409.

DOI:10.1097/RLU.0000000000002409

PMID:30516664

Abstract

Here we report on the treatment of a 38-year-old woman with primary cutaneous γδT-cell lymphoma, which is a rare subset of cutaneous T-cell lymphoma. She presented with multiple subtle subcutaneous nodules, which were not clearly observed on computed tomography scans or after biopsy. However, F-fluorodeoxyglucose positron emission tomography (F-FDG-PET) accurately detected small cutaneous lesions. She achieved a second complete remission, as demonstrated by F-FDG-PET performed after pralatrexate infusion.

摘要

我们在此报告一例 38 岁女性原发性皮肤 γδT 细胞淋巴瘤的治疗情况，该病为皮肤 T 细胞淋巴瘤的一个罕见亚型。患者表现为多个细微的皮下结节，在计算机断层扫描或活检后均无法明确观察到。然而，氟-18 氟代脱氧葡萄糖正电子发射断层扫描（F-FDG-PET）准确地检测到了较小的皮肤病变。在接受普拉曲沙输注后进行的 F-FDG-PET 检查显示，患者达到了第二次完全缓解。