Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS.
Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Istituto di Ematologia.
Clin Nucl Med. 2019 Feb;44(2):e87-e89. doi: 10.1097/RLU.0000000000002393.
A 75-year-old man, who had been diagnosed with small lymphocytic lymphoma with cervical localization, underwent F-FDG PET/CT with iodinated contrast medium due to the appearance of cervical swelling suspected of illness relapse. PET/CT revealed intense F-FDG uptake in multiple cervical and subdiaphragmatic lymph nodes and in the left parotid. Moreover, diffuse uptake and wall thickening of the colon were evident; endoscopy with biopsy revealed a diffuse large B-cell lymphoma. Transformation into a more aggressive lymphoma occurs in 2% to 8% of small lymphocytic lymphoma, the so-called Richter syndrome. Extranodal localization in the sigmoid colon is an extremely rare site for transformed lymphoma.
一位 75 岁男性，曾被诊断为伴有颈部定位的小淋巴细胞淋巴瘤，因疑似疾病复发出现颈部肿胀而接受 F-FDG PET/CT 检查，同时使用碘造影剂。PET/CT 显示多个颈部和膈肌下淋巴结以及左侧腮腺摄取 F-FDG 明显增加。此外，结肠弥漫性摄取和壁增厚明显；内镜活检显示弥漫性大 B 细胞淋巴瘤。2%至 8%的小淋巴细胞淋巴瘤会转化为侵袭性更强的淋巴瘤，即所谓的里希特综合征。乙状结肠的结外定位是转化性淋巴瘤极为罕见的部位。
