From the Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia.
Clin Nucl Med. 2019 Feb;44(2):145-147. doi: 10.1097/RLU.0000000000002388.
Two patients with diffuse large B-cell lymphoma relapsing as neurolymphomatosis diagnosed on FDG PET/CT are presented. Both patients were treated initially with chemotherapy and had a complete metabolic response. Patient 1 represented with lower-limb pain. An FDG PET/CT demonstrated intense uptake throughout the sciatic nerves bilaterally extending distally with relapse confirmed on biopsy. Patient 2 represented to hospital with worsening mobility, neuropathic pain, and facial asymmetry. An FDG PET/CT demonstrated relapse within the spinal cord, left sciatic nerve, and facial nerve branches. Neurolymphomatosis is an uncommon finding on FDG PET/CT and can be the only site of relapse.
现介绍 2 例经 FDG PET/CT 诊断为神经淋巴病的弥漫性大 B 细胞淋巴瘤复发患者。这两名患者最初均接受化疗治疗，代谢完全缓解。患者 1 表现为下肢疼痛。FDG PET/CT 显示双侧坐骨神经广泛摄取，远端延伸，活检证实复发。患者 2 因运动障碍、神经痛和面部不对称就诊。FDG PET/CT 显示脊髓、左侧坐骨神经和面神经分支复发。神经淋巴病在 FDG PET/CT 上是一种罕见的表现，并且可能是唯一的复发部位。
