From the Departments of *Nuclear Medicine and PET and †Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Clin Nucl Med. 2015 May;40(5):e290-2. doi: 10.1097/RLU.0000000000000632.
Neurolymphomatosis, a rare extranodal lymphoma, may involve the cranial nerves, peripheral nerves, spinal nerve roots, or nerve plexus. F-FDG PET/CT however shows increased FDG uptake in the nerves but is not specific for malignancy. We report a patient with neurolymphomatosis who underwent F-FDG PET/CT and F-fluorothymidine PET/CT where both the scans showed increased tracer uptake in the right sciatic nerve, proven later as neurolymphomatosis on nerve biopsy. Furthermore, the F-FDG avid mediastinal lymph nodes did not show F-fluorothymidine avidity, suggesting an inflammatory etiology.
神经淋巴瘤病是一种罕见的结外淋巴瘤，可累及颅神经、周围神经、脊神经根或神经丛。然而，氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）显示神经内 FDG 摄取增加，但不能特异性诊断恶性肿瘤。我们报告了 1 例神经淋巴瘤病患者，行 F-FDG PET/CT 和 F-氟代胸苷 PET/CT 检查，两种扫描均显示右侧坐骨神经摄取示踪剂增加，随后神经活检证实为神经淋巴瘤病。此外，氟代脱氧葡萄糖摄取的纵隔淋巴结不摄取 F-氟代胸苷，提示炎症病因。
