Najem Sinann Al, Groll Andreas, Schmermund Axel, Nowak Bernd, Voigtländer Thomas, Kaltenbach Ulrike, Dohmann Peter, Andresen Dietrich, Scharhag Jürgen
German Heart Foundation, Frankfurt, Germany,
Institute of Sports and Preventive Medicine, Saarbrücken, Germany,
Vasc Health Risk Manag. 2018 Nov 9;14:361-369. doi: 10.2147/VHRM.S179798. eCollection 2018.
A total of 6,500 to 8,000 steps per day are recommended for cardiovascular secondary prevention. The aim of this research was to examine how many steps per day patients achieve during ambulant cardiac rehabilitation (CR), and if there is a correlation between the number of steps and physical and cardiological parameters.
In all, 192 stable CR patients were included and advised for sealed pedometry. The assessed parameters included maximum working capacity and heart rate, body mass index (BMI), New York Heart Association (NYHA) class, ejection fraction (EF), coronary artery disease status, beta-blocker medication, age, sex, smoking behavior, and laboratory parameters. A regularized regression approach called least absolute shrinkage and selection operator (LASSO) was used to detect a small set of explanatory variables associated with the response for steps per day. Based on these selected covariates, a sparse additive regression model was fitted.
The model noted that steps per day had a strong positive correlation with maximum working capacity (=0.001), a significant negative correlation with higher age (=0.01) and smoking (smoker: <0.05; ex-smoker: =0.01), a positive correlation with high-density lipoprotein (HDL), and a negative correlation with beta-blockers. Correlation between BMI and walking activity was nonlinear (BMI 18.5-24: 7,427±2,730 steps per day; BMI 25-29: 6,448±2,393 steps/day; BMI 30-34: 6,751±2,393 steps per day; BMI 35-39: 5,163±2,574; BMI >40: 6,077±1,567).
Walking activity during CR is reduced in patients who are unfit, older, smoke, or used to smoke. In addition to training recommendations, estimated steps per day during CR could be seen as a baseline orientation that helps patients to stay generally active or even to increase activity after CR.
心血管疾病二级预防建议每日步数为6500至8000步。本研究旨在调查心脏康复(CR)期间患者每日达到的步数,以及步数与身体和心脏参数之间是否存在相关性。
总共纳入192例病情稳定的CR患者,并建议其使用密封式计步器。评估参数包括最大工作能力和心率、体重指数(BMI)、纽约心脏协会(NYHA)分级、射血分数(EF)、冠状动脉疾病状况、β受体阻滞剂用药情况、年龄、性别、吸烟行为和实验室参数。使用一种名为最小绝对收缩和选择算子(LASSO)的正则化回归方法来检测与每日步数响应相关的一小部分解释变量。基于这些选定的协变量,拟合了一个稀疏加法回归模型。
该模型指出,每日步数与最大工作能力呈强正相关(=0.001),与较高年龄(=0.01)和吸烟呈显著负相关(吸烟者:<0.05;既往吸烟者:=0.01),与高密度脂蛋白(HDL)呈正相关,与β受体阻滞剂呈负相关。BMI与步行活动之间的相关性是非线性的(BMI 18.5 - 24:每日7427±2730步;BMI 25 - 29:每日6448±2393步;BMI 30 - 34:每日6751±2393步;BMI 35 - 39:5163±2574步;BMI>40:6077±1567步)。
身体不健康、年龄较大、吸烟或既往吸烟患者在CR期间的步行活动减少。除了训练建议外,CR期间每日估计步数可被视为一种基线导向,有助于患者保持总体活动,甚至在CR后增加活动量。