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影响心力衰竭患者在进行基于运动的心脏康复后步行能力变化的因素。

Factors influencing change in walking ability in patients with heart failure undergoing exercise-based cardiac rehabilitation.

机构信息

Department of Health Sciences, University of York, York, UK.

Department of Health Sciences, University of York, York, UK.

出版信息

Int J Cardiol. 2018 Oct 1;268:162-165. doi: 10.1016/j.ijcard.2018.05.021. Epub 2018 May 18.

Abstract

OBJECTIVES

Exercise-based cardiac rehabilitation (CR) is an effective intervention for patients with heart failure (HF), in which one of the main targets is to increase physical capacity. In the HF population this is traditionally assessed using distance covered during a walking test. This study aims to establish the extent to which change in walking ability, in HF patients attending CR, is determined by patient characteristics and service provision.

METHODS

The study utilised routine clinical data from the National Audit of Cardiac Rehabilitation to perform a robust analysis. Change, in metres, between pre- and post-CR six-minute walk tests was calculated. Multivariate linear regression models were used to explore the relationship between patient characteristics, service-level variables, and change in metres walked.

RESULTS

Complete and valid data from 633 patients was analysed, and a mean change of 51.30 m was calculated. Female gender (-34.13 m, p = 0.007), being retired (-36.41 m, p = 0.001) and being married/in a relationship (-32.54 m, p = 0.023) were all significant negative predictors of change. There was an additional negative relationship with body mass index (BMI) whereby for every unit increase in BMI, predicted change reduces by 2.48 m (p = 0.006).

CONCLUSIONS

This study identified significant patient-level characteristics strongly associated with limited improvement in walking ability following CR. Improving physical capacity is a core component of CR, therefore services should aim to account for baseline characteristics identified in this study as part of tailoring the CR intervention around the individual. Pre- and post-CR physical capacity assessments, which constitute minimum standards for CR, are worryingly low and should be given high priority.

摘要

目的

基于运动的心脏康复(CR)是心力衰竭(HF)患者的有效干预措施,其主要目标之一是提高身体能力。在 HF 人群中,这通常是通过步行测试中覆盖的距离来评估的。本研究旨在确定 HF 患者在接受 CR 时步行能力的变化在多大程度上取决于患者特征和服务提供。

方法

该研究利用国家心脏康复审计的常规临床数据进行了稳健分析。计算 CR 前后六分钟步行测试中距离的变化(以米为单位)。使用多元线性回归模型探索患者特征、服务水平变量与步行距离变化之间的关系。

结果

对 633 名患者的完整和有效数据进行了分析,计算出平均变化为 51.30m。女性(-34.13m,p=0.007)、退休(-36.41m,p=0.001)和已婚/恋爱(-32.54m,p=0.023)的性别均为显著负预测因子。体重指数(BMI)也存在额外的负相关关系,即 BMI 每增加一个单位,预测的变化减少 2.48m(p=0.006)。

结论

本研究确定了与 CR 后步行能力改善有限密切相关的重要患者特征。提高身体能力是 CR 的核心组成部分,因此服务应旨在根据本研究确定的基线特征进行调整,以适应个体的 CR 干预措施。CR 的最低标准——CR 前后的身体能力评估,令人担忧地低,应给予高度重视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90fb/6069635/29244bd6c21e/gr1.jpg

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