Arai E, Ikeda S, Itoh S, Katayama I
Department of Pathology, Saitama Medical School, Japan.
Am J Clin Pathol. 1988 Oct;90(4):459-64. doi: 10.1093/ajcp/90.4.459.
A 68-year-old Japanese man with a chief complaint of eczema-like dermatosis was diagnosed as having B-cell hairy cell leukemia (HCL) by demonstration of hairy cells in the skin lesions as well as in blood and bone marrow. He was treated with alpha-interferon, resulting in disappearance of skin lesions and reduction of his massive splenomegaly from 18 to 5 cm in about 14 months. Although specific skin lesions in HCL, shown by a review of the literature to occur in about 8% of cases, are not as uncommon as generally assumed, it is rare for HCL to present with specific skin lesions, the present case being only the second of its type mentioned in the literature.
一名68岁的日本男性，以湿疹样皮肤病为主诉，经在皮肤病变以及血液和骨髓中发现毛细胞，被诊断为B细胞毛细胞白血病（HCL）。他接受了α干扰素治疗，约14个月后皮肤病变消失，巨大脾脏从18厘米缩小至5厘米。尽管文献回顾显示HCL中的特异性皮肤病变约在8%的病例中出现，并非如普遍认为的那样罕见，但HCL以特异性皮肤病变为表现仍很罕见，本病例是文献中提及的该类型的第二例。
