Ng M H, Tsang S S, Ng H K, Sriskandavarman V, Feng C S
Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T.
Hum Pathol. 1991 Dec;22(12):1298-302. doi: 10.1016/0046-8177(91)90117-8.
Hairy cell leukemia (HCL) was diagnosed in a 71-year-old Chinese man. His clinical presentation and the characteristics of the hairy cells were typical of classic HCL. However, extreme leukocytosis (195 to 323 x 10(9) cells/L) in peripheral blood was in striking contrast. This leukocytosis, which was much more pronounced than any of the reported cases of HCL with leukocytosis, was associated with leukostasis in the cerebral vasculature and was causally related to a massive intracerebral hemorrhage and death. This mode of death in HCL has not been reported previously.
一名71岁的中国男性被诊断为毛细胞白血病（HCL）。他的临床表现和毛细胞特征符合典型HCL。然而，外周血中出现了极度白细胞增多（195至323×10⁹个细胞/L），这形成了鲜明对比。这种白细胞增多比任何已报道的HCL合并白细胞增多的病例都更为显著，与脑血管系统的白细胞淤滞有关，并直接导致了大规模脑出血和死亡。HCL这种死亡方式此前尚未见报道。
