Dermatology Clinic - Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
J Eur Acad Dermatol Venereol. 2019 May;33(5):954-958. doi: 10.1111/jdv.15388. Epub 2019 Jan 9.
The clinical and dermoscopic changes of melanocytic nevi under the effects of photo-epilation are poorly known.
Prospective study on clinical and dermatoscopic effects of photoe-pilation on melanocytic nevi.
Eighteen patients exposed to photo-epilation gave consent to a follow-up programme from 2008 to 2017 at the Videodermatoscopic Office of the Dermatology Clinic of Cagliari (Italy), with clinical and dermoscopic assessment.
A mean 2-year follow-up was recorded for 73 lesions. The most frequent clinical change was nevi colour, clearer than basal pictures, sometimes with increased pigmentation at the periphery, or residual islands of pigmentation, with vanishing borders. Acute burn with crusting was noted in few cases. Only one case showed progressive growth. Corresponding dermoscopic findings were bleaching of nevi, followed by pigment network disruption, appearance of white structureless areas and grey-blue globules. Complete regression occurred in 32.8% of the lesions. The growing nevus was characterized by peripheral globules. Excision for histopathological examination showed a compound nevus with mild atypia.
Although malignant modifications of nevi after photo-epilation have not been described, the clinical and dermoscopic changes we observed suggest to extend the follow for more than 24 months, as the potential long-term adverse effects of photo-epilation on melanocytic nevi are unknown.
光脱毛对黑素细胞痣的临床和皮肤镜学改变知之甚少。
前瞻性研究光脱毛对黑素细胞痣的临床和皮肤镜学效果。
2008 年至 2017 年，意大利卡利亚里皮肤科诊所的视频皮肤镜办公室对 18 名接受光脱毛的患者进行了随访，进行了临床和皮肤镜评估。
对 73 处病变进行了平均 2 年的随访。最常见的临床变化是痣的颜色比基础图像更清晰，有时边缘色素沉着增加，或残留色素岛，边界消失。少数病例出现急性烧伤伴结痂。只有 1 例显示进行性生长。相应的皮肤镜发现是痣的褪色，随后是色素网状结构的破坏，出现白色无结构区域和灰蓝色小球。32.8%的病变完全消退。生长的痣的特征是边缘的小球。切除进行组织病理学检查显示复合痣伴轻度非典型性。
尽管尚未描述光脱毛后痣的恶性改变，但我们观察到的临床和皮肤镜学变化表明，需要延长随访时间超过 24 个月，因为光脱毛对黑素细胞痣的潜在长期不良影响尚不清楚。
