Spellacy W N, Ellingson A B, Kotlik A, Tsibris J C
Department of Obstetrics and Gynecology, University of Illinois College of Medicine.
Am J Obstet Gynecol. 1988 Oct;159(4):877-9. doi: 10.1016/s0002-9378(88)80159-5.
Thirty-five women with normal carbohydrate metabolism were administered a 3-hour oral glucose tolerance test before and after 3 months' use of a triphasic oral contraceptive that contained ethinyl estradiol and norethindrone. The results show no significant change in either the plasma glucose or the insulin values. This is the first published study with regard to this type of triphasic oral contraceptive, and the study supports claims of the preparation's improved safety.
35名碳水化合物代谢正常的女性在使用含有炔雌醇和炔诺酮的三相口服避孕药3个月前后，分别接受了一次3小时口服葡萄糖耐量试验。结果显示，血浆葡萄糖值和胰岛素值均无显著变化。这是关于此类三相口服避孕药的首篇发表研究，该研究支持了这种制剂安全性有所提高的说法。
