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间充质干细胞的衰老:对再生医学的影响。

Aging of mesenchymal stem cells: Implication in regenerative medicine.

作者信息

Yang Yueh-Hsun Kevin

机构信息

Grove School of Engineering, The City University of New York - the City College, New York, NY 10031, USA.

出版信息

Regen Ther. 2018 Nov 3;9:120-122. doi: 10.1016/j.reth.2018.09.002. eCollection 2018 Dec.

Abstract

Multipotent mesenchymal stem cells (MSCs) represent a great candidate for various clinical applications including regenerative medicine. However, aging both and can significantly compromise MSC characteristics and performance. This paper highlights current thoughts on senescence-induced damage to MSCs that should be considered prior to their use for regeneration of different cells, tissues or organs.

摘要

多能间充质干细胞(MSCs)是包括再生医学在内的各种临床应用的理想候选者。然而,衰老和 都可能显著损害MSCs的特性和性能。本文重点介绍了目前关于衰老诱导的MSCs损伤的观点,这些观点在将MSCs用于不同细胞、组织或器官的再生之前应予以考虑。

需注意,原文中“aging both and ”表述不完整,存在信息缺失。

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Aging of mesenchymal stem cells: Implication in regenerative medicine.间充质干细胞的衰老:对再生医学的影响。
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