Small J, Wallace R G, Millar R, Woolfson A D, McCafferty D F
Plastic Surgery Department, Ulster Hospital, Dundonald.
Br J Plast Surg. 1988 Sep;41(5):539-43. doi: 10.1016/0007-1226(88)90014-8.
The use of a novel percutaneous anaesthetic preparation for the pain-free cutting of split skin grafts has been assessed in a series of 80 patients, age range 12 to 96 years. The technique was completely successful in 80% of these cases, with complete analgesia established within one hour of initial application. Duration of anaesthesia was such that pain-free cutting of the skin was possible up to 5 hours after initial application of the preparation. Failures of the technique were largely attributed to a loss of anaesthetic potency in the preparation, application of an inadequate amount to the site or patient anxiety. The use of the percutaneous anaesthetic preparation was found to offer considerable advantages over conventional infiltration anaesthesia for this type of surgery. Several additional surgical applications of percutaneous anaesthesia are also considered.
在80例年龄范围为12至96岁的患者中，对一种用于无痛切取断层皮片的新型经皮麻醉制剂进行了评估。该技术在80%的病例中完全成功，初次应用后一小时内即可建立完全镇痛。麻醉持续时间使得在初次应用制剂后长达5小时内都可以进行无痛皮肤切割。该技术的失败主要归因于制剂中麻醉效力的丧失、在手术部位涂抹的量不足或患者焦虑。结果发现，对于这类手术，使用经皮麻醉制剂比传统浸润麻醉具有相当大的优势。还考虑了经皮麻醉的其他几种手术应用。
