Department of Pharmacy Practice, Presbyterian College School of Pharmacy, Clinton, South Carolina.
Department of Internal Medicine, Medical College of Georgia - Southwest Clinical Campus, Albany, Georgia; Department of Cardiology,.
Am J Med Sci. 2019 Mar;357(3):255-257. doi: 10.1016/j.amjms.2018.10.011. Epub 2018 Oct 30.
Marijuana is the most commonly used illicit drug in the world. Over the last decade, the potency of marijuana has increased tremendously. Its use is associated with harmful health consequences including adverse cardiovascular effects, such as arrhythmias, myocardial infarction, cardiomyopathy and stroke. It has been reported to cause bradycardia. This report describes the case of a 51-year-old female with no significant past medical history who presented with complete heart block due to chronic marijuana use, requiring a permanent pacemaker. To our knowledge, this is the first reported case of complete heart block due to chronic marijuana use. Advanced conduction system abnormalities can be a potential complication of chronic marijuana use, which the physicians need to be aware of. With increasing push for medical marijuana, physicians are likely to encounter more of such cases.
大麻是世界上使用最广泛的非法药物。在过去的十年中，大麻的效力大大增强。它的使用与有害的健康后果有关，包括心血管不良影响，如心律失常、心肌梗死、心肌病和中风。据报道，它会导致心动过缓。本报告描述了一例 51 岁女性的病例，她没有明显的既往病史，因长期使用大麻导致完全性心脏阻滞，需要植入永久性起搏器。据我们所知，这是首例因长期使用大麻导致完全性心脏阻滞的报告。慢性大麻使用可导致潜在的高级传导系统异常，这是医生需要注意的问题。随着医用大麻的推广，医生可能会遇到更多这样的病例。
