Van Keer Jan M
Department of Cardiology, University Hospitals Leuven, Belgium.
Department of Microbiology, Immunology and Transplantation, KU Leuven, University of Leuven, Belgium.
Case Rep Emerg Med. 2019 Sep 16;2019:5037356. doi: 10.1155/2019/5037356. eCollection 2019.
Cannabis (marijuana) is the most widely consumed illicit drug in Europe. However, many are unaware of its potential cardiovascular side effects.
A 19-year-old man presented to the emergency department with palpitations and presyncope after smoking cannabis. A third-degree atrioventricular block (complete heart block) was diagnosed. We believe cannabis exposure to have been the likely cause. Extensive work-up-including Borrelia and auto-immune serology, CT coronary angiography, magnetic resonance imaging, and electrophysiological study-was negative. The patient was initially treated with IV isoprenaline. Within one day, the bradycardia spontaneously resolved. The patient was advised to quit using cannabis. No further therapy was initiated. We discuss the clinical presentation, pathophysiology, and evidence from the literature linking cannabis exposure to bradycardia.
We describe a case of third-degree atrioventricular block after cannabis use. Emergency physicians should be aware of the potential cardiovascular side effects of this drug.
大麻（ marijuana）是欧洲消费最广泛的非法药物。然而，许多人并未意识到其潜在的心血管副作用。
一名19岁男性在吸食大麻后因心悸和接近晕厥状态被送往急诊科。诊断为三度房室传导阻滞（完全性心脏传导阻滞）。我们认为大麻暴露很可能是病因。包括伯氏疏螺旋体和自身免疫血清学、CT冠状动脉造影、磁共振成像以及电生理研究在内的全面检查均为阴性。患者最初接受静脉注射异丙肾上腺素治疗。一天内，心动过缓自行缓解。建议患者停止使用大麻。未启动进一步治疗。我们讨论了临床表现、病理生理学以及文献中关于大麻暴露与心动过缓相关的证据。
我们描述了一例使用大麻后发生三度房室传导阻滞的病例。急诊医生应意识到这种药物潜在的心血管副作用。
