Environmental and Occupational Health Surveillance Program, New Jersey Department of Health, Trenton, NJ, USA.
Child and Adolescent Health Program, New Jersey Department of Health, Trenton, NJ, USA.
Environ Res. 2019 Feb;169:409-416. doi: 10.1016/j.envres.2018.11.016. Epub 2018 Nov 14.
As blood lead levels have decreased over time, the relative contributions of alternative lead sources warrant further examination. Much attention has been paid to the relative contribution of lead in drinking water, particularly after the discovery of contaminated drinking water in Flint, Michigan which has also renewed interest in the persistent socioeconomic and racial disparities in children's exposure to lead. As the environmental sources of lead exposure are shifting in importance over time, we decided to examine how demographic, socioeconomic, and environmental factors may confound or interact with each other, and whether these relationships have changed over time. The study population included all New Jersey resident children aged 6-26 months with at least one blood lead specimen collected between 2000 and 2004 (n = 288,758) or 2010 and 2014 (n = 326,530). Reported 90th percentile water lead data (in parts per billion) was summarized annually for each water system statewide. Children's blood lead levels have decreased over time from a statewide geometric mean of 2.47 µg/dL (95% CI 2.46, 2.48) between 2000 and 2004 to 1.57 µg/dL (95% CI 1.57, 1.57) between 2010 and 2014. Individual-level factors of child's age and season of blood draw and area-based measures of race, older housing, and poverty were predictors of children's blood lead levels. Conclusions regarding area-based measure of Hispanic ethnicity are limited and require further research. The narrow range and low levels of area-based lead concentrations in drinking water limits the ability to detect associations with blood lead levels. Racial disparities in blood lead continue to persist but economic disparities may be narrowing as blood lead concentrations continue to decline.
随着时间的推移,血液中铅含量逐渐降低,其他铅污染源的相对贡献值得进一步研究。人们越来越关注饮用水中的铅含量,尤其是在密歇根州弗林特市发现受污染的饮用水后,这也重新引发了人们对儿童接触铅的持续存在的社会经济和种族差异的关注。随着环境中铅暴露源的重要性不断变化,我们决定研究人口统计学、社会经济学和环境因素如何相互混淆或相互作用,以及这些关系是否随时间发生变化。研究人群包括所有新泽西州居住的年龄在 6-26 个月、2000 年至 2004 年间(n=288758)或 2010 年至 2014 年间(n=326530)至少采集过一次血样的儿童。每年全州范围内汇总报告了每个供水系统的 90 百分位水中铅含量(十亿分之几)。儿童血铅水平随时间逐渐降低,2000 年至 2004 年间全州几何平均水平为 2.47μg/dL(95%置信区间 2.46,2.48),2010 年至 2014 年间为 1.57μg/dL(95%置信区间 1.57,1.57)。儿童年龄和采血季节等个体因素以及种族、老旧住房和贫困等基于地区的指标是儿童血铅水平的预测因素。关于西班牙裔种族的基于地区的衡量标准的结论是有限的,需要进一步研究。饮用水中基于地区的铅浓度范围狭窄且水平较低,限制了检测与血铅水平之间关联的能力。血铅的种族差异仍然存在,但随着血铅浓度的持续下降,经济差异可能正在缩小。