Lyngberg K, Danneskiold-Samsøe B, Halskov O
Department of Rheumatology, Københavns Kommunes Hvidovre Hospital, University of Copenhagen, Denmark.
Clin Exp Rheumatol. 1988 Jul-Sep;6(3):253-60.
For decades, physical training of rheumatoid arthritis (RA)-patients has been controversial, especially for patients with active disease. The aim of this study was to investigate whether RA-patients could receive graduated training without increasing the activity of the disease. In a controlled cross-over study the effect of graduated progressive training has been evaluated in 18 RA-patients with moderately active disease. The training was performed twice weekly with aerobic conditioning and strength exercises progressing to strenuous exercises over an 8-week period. The design was a crossover project with two groups obtained by minimisation. After training the patients had significantly fewer swollen joints than before. Training of the muscles acting over the swollen joints resulted in more than a 35% decrease in the number of swollen joints. The hemoglobin level increased significantly after the training period. The erythrocyte sedimentation rate, the complement factor C3d, and the number of sore joints remained unchanged. A decrease in the need for medicine was non-significant. From this study it appears that RA-patients with some activity are trainable without aggravating the disease, even in the chronically swollen joints. The rheumatoid arthritis activity decreased with fewer swollen joints and higher hemoglobin level after training.
几十年来，类风湿关节炎（RA）患者的体育训练一直存在争议，尤其是对于疾病处于活动期的患者。本研究的目的是调查RA患者能否接受循序渐进的训练而不增加疾病活动度。在一项对照交叉研究中，对18例中度活动期疾病的RA患者进行了循序渐进的渐进性训练效果评估。训练每周进行两次，包括有氧调节和力量练习，在8周内逐渐过渡到剧烈运动。该设计是一个通过最小化分组得到两组的交叉项目。训练后，患者肿胀关节的数量明显少于训练前。对肿胀关节周围肌肉的训练使肿胀关节数量减少了35%以上。训练期后血红蛋白水平显著升高。红细胞沉降率、补体因子C3d和疼痛关节数量保持不变。药物需求的减少不显著。从这项研究看来，即使是慢性肿胀关节的、有一定活动度的RA患者也可进行训练而不加重病情。训练后，类风湿关节炎活动度降低，肿胀关节减少，血红蛋白水平升高。
