Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
PLoS One. 2018 Dec 7;13(12):e0208848. doi: 10.1371/journal.pone.0208848. eCollection 2018.
To compare the surgical outcomes between pre- and full-term patients with exotropia and to examine the factors associated with surgical outcomes.
This retrospective study included 48 pre- and 432 full-term patients with basic-type exotropia who underwent unilateral or bilateral lateral rectus muscle (ULR or BLR) recession. Preoperative characteristics and surgical outcomes were compared between the pre- and full-term infants. Additionally, factors affecting the surgical outcomes were evaluated in all patients.
The preoperative characteristics were significantly different between the pre- and full-term groups in terms of neurodevelopmental disabilities (p = 0.020). There were no significant differences between the pre- and full-term groups in terms of the success, overcorrection, and recurrence rates after the mean follow-up period of 34.6 ± 13.9 months (p = 0.697). The major cause of surgical failure was recurrence in both groups. Pre-term birth was not a risk factor for overcorrection and recurrence. However, regardless of the pre- or full-term birth status, the presence of neurodevelopmental disabilities significantly affected final overcorrection (p = 0.004).
Pre-term patients with exotropia showed similar surgical outcomes to full-term controls. The presence of neurodevelopmental disabilities was a risk factor for final overcorrection.
比较术前和足月的外斜视患者的手术结果，并探讨与手术结果相关的因素。
本回顾性研究纳入了 48 例基本型外斜视的术前和 432 例足月患者，均行单侧或双侧外直肌（ULR 或 BLR）后退术。比较术前特征和手术结果在早产儿和足月儿之间的差异。此外，评估所有患者的手术结果的影响因素。
在神经发育障碍方面，术前特征在早产儿和足月儿之间存在显著差异（p = 0.020）。在平均随访 34.6 ± 13.9 个月后，成功率、过矫正率和复发率在早产儿和足月儿之间无显著差异（p = 0.697）。手术失败的主要原因是两组的复发。早产儿出生不是过矫正和复发的危险因素。然而，无论早产儿或足月儿出生状态如何，神经发育障碍的存在显著影响最终的过矫正（p = 0.004）。
外斜视的早产儿患者的手术结果与足月对照组相似。神经发育障碍的存在是最终过矫正的危险因素。
