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斜视患者术前与足月产儿手术效果的比较。

A comparison of surgical outcomes between pre-and full-term patients with exotropia.

机构信息

Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Chuncheon, Korea.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

PLoS One. 2018 Dec 7;13(12):e0208848. doi: 10.1371/journal.pone.0208848. eCollection 2018.

Abstract

PURPOSE

To compare the surgical outcomes between pre- and full-term patients with exotropia and to examine the factors associated with surgical outcomes.

METHODS

This retrospective study included 48 pre- and 432 full-term patients with basic-type exotropia who underwent unilateral or bilateral lateral rectus muscle (ULR or BLR) recession. Preoperative characteristics and surgical outcomes were compared between the pre- and full-term infants. Additionally, factors affecting the surgical outcomes were evaluated in all patients.

RESULTS

The preoperative characteristics were significantly different between the pre- and full-term groups in terms of neurodevelopmental disabilities (p = 0.020). There were no significant differences between the pre- and full-term groups in terms of the success, overcorrection, and recurrence rates after the mean follow-up period of 34.6 ± 13.9 months (p = 0.697). The major cause of surgical failure was recurrence in both groups. Pre-term birth was not a risk factor for overcorrection and recurrence. However, regardless of the pre- or full-term birth status, the presence of neurodevelopmental disabilities significantly affected final overcorrection (p = 0.004).

CONCLUSIONS

Pre-term patients with exotropia showed similar surgical outcomes to full-term controls. The presence of neurodevelopmental disabilities was a risk factor for final overcorrection.

摘要

目的

比较术前和足月的外斜视患者的手术结果,并探讨与手术结果相关的因素。

方法

本回顾性研究纳入了 48 例基本型外斜视的术前和 432 例足月患者,均行单侧或双侧外直肌(ULR 或 BLR)后退术。比较术前特征和手术结果在早产儿和足月儿之间的差异。此外,评估所有患者的手术结果的影响因素。

结果

在神经发育障碍方面,术前特征在早产儿和足月儿之间存在显著差异(p = 0.020)。在平均随访 34.6 ± 13.9 个月后,成功率、过矫正率和复发率在早产儿和足月儿之间无显著差异(p = 0.697)。手术失败的主要原因是两组的复发。早产儿出生不是过矫正和复发的危险因素。然而,无论早产儿或足月儿出生状态如何,神经发育障碍的存在显著影响最终的过矫正(p = 0.004)。

结论

外斜视的早产儿患者的手术结果与足月对照组相似。神经发育障碍的存在是最终过矫正的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/6286133/c65a918fd3e6/pone.0208848.g001.jpg

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