Nagayoshi Yasuhiro, Nakaura Takeshi, Awai Kazuo, Oishi Satoru, Arima Yuichiro, Sugiyama Seigo, Kawano Hiroaki, Kuroda Yutaka, Yamashita Yasuyuki, Ogawa Hisao
Department of Community Medicine, Kumamoto University Hospital, 1-1-1 Honjo, Kumamoto City 860-8556, Japan.
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan.
J Cardiol Cases. 2011 Aug 9;4(2):e71-e75. doi: 10.1016/j.jccase.2011.06.008. eCollection 2011 Oct.
Tako-tsubo cardiomyopathy is characterized by transient left ventricular contractile dysfunction. The precise etiology of tako-tsubo cardiomyopathy remains to be elucidated. We performed coronary angiography in two patients with tako-tsubo cardiomyopathy and evaluated the coronary microcirculation by digital subtraction angiography (DSA). In the acute phase of tako-tsubo cardiomyopathy, coronary DSA demonstrated severely reduced perfusion in the apex. Follow-up DSA showed the restoration of normal myocardial perfusion in the apex. Coronary DSA can simultaneously depict the coronary vessels and myocardial perfusion abnormalities. Furthermore, DSA can also show the relationship between the perfusion territory of the coronary arteries and the region of impaired myocardial perfusion. This technique might support the central role of microcirculation disturbance in tako-tsubo cardiomyopathy.
应激性心肌病的特征是短暂性左心室收缩功能障碍。应激性心肌病的确切病因仍有待阐明。我们对两名应激性心肌病患者进行了冠状动脉造影,并通过数字减影血管造影(DSA)评估了冠状动脉微循环。在应激性心肌病的急性期,冠状动脉DSA显示心尖部灌注严重减少。随访DSA显示心尖部心肌灌注恢复正常。冠状动脉DSA可以同时描绘冠状动脉血管和心肌灌注异常。此外,DSA还可以显示冠状动脉灌注区域与心肌灌注受损区域之间的关系。这项技术可能支持微循环障碍在应激性心肌病中起核心作用。