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一例患有抗磷脂综合征的冠状动脉疾病患者出现反复支架血栓形成。

A case of coronary artery disease with antiphospholipid syndrome that showed repeated stent thrombosis.

作者信息

Mito Takahiro, Miura Shin-Ichiro, Takada Kohei, Koyoshi Rie, Morii Joji, Sugihara Makoto, Mori Ken, Iwata Atsushi, Sako Hideto, Nishikawa Hiroaki, Kawamura Akira, Saku Keijiro

机构信息

Department of Cardiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.

出版信息

J Cardiol Cases. 2011 Jul 27;4(2):e80-e86. doi: 10.1016/j.jccase.2011.06.006. eCollection 2011 Oct.

Abstract

A 55-year-old man with severe chest pain was hospitalized for acute coronary syndrome. Coronary angiography revealed total occlusion of his left anterior descending coronary artery, which was successfully recanalized by percutaneous coronary intervention (PCI). However, the patient subsequently experienced subacute stent thrombosis, restenosis in the stent, and frequent thrombosis in PCI toward restenosis. Primary antiphospholipid syndrome should be considered as a possible cause of repeated stent thrombosis, and, if salvage by PCI is impossible, salvage by coronary artery bypass graft should be considered.

摘要

一名55岁胸痛严重的男性因急性冠状动脉综合征住院。冠状动脉造影显示其左前降支冠状动脉完全闭塞,经皮冠状动脉介入治疗(PCI)成功使其再通。然而,该患者随后出现亚急性支架血栓形成、支架内再狭窄以及针对再狭窄的PCI术中频繁血栓形成。原发性抗磷脂综合征应被视为反复发生支架血栓形成的可能原因,并且,如果无法通过PCI挽救,则应考虑通过冠状动脉旁路移植术进行挽救。

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Antiphospholipid antibodies and atherosclerosis.抗磷脂抗体与动脉粥样硬化
Clin Immunol. 2004 Aug;112(2):183-9. doi: 10.1016/j.clim.2004.02.016.

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