Hardegree Evan L, Tweet Marysia S, Hayes Sharonne N, Gulati Rajiv, Kane Garvan C
Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
J Cardiol Cases. 2012 Mar 6;5(2):e69-e72. doi: 10.1016/j.jccase.2012.01.003. eCollection 2012 Apr.
Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.
自发性冠状动脉夹层（SCAD）是健康年轻个体胸痛和心肌梗死的一种罕见且可能致命的病因。它更常见于女性，并且与妊娠和使用口服避孕药时激素诱导的结缔组织变化有关。我们报告了一例既往健康的39岁女性病例，其患有多支血管SCAD，与近期因不孕症接受克罗米芬和促性腺激素治疗有关，这是之前未报道过的关联，我们认为这应列入此类胸痛或心肌梗死患者的鉴别诊断中。
