一名老年男性在接受卡介苗膀胱灌注治疗膀胱癌时骨髓增生异常综合征出现短暂自发缓解：病例报告及文献复习

Transitory Spontaneous Remission of Myelodysplasia in an Elderly Man while Receiving Intravesical Bacillus Calmette-Guérin for Bladder Cancer: A Case Report and Review of the Literature.

作者信息

Murray Nigel P, Fuentealba Cynthia, Salazar Isidora, Salazar Aníbal, Lopez Marco Antonio, Minzer Simona

机构信息

Consultant Hemologist, Depto. Medicine, Hospital de Carabineros de Chile, Simón Bolívar 2200, Ñuñoa 7770199, Santiago, Chile.

Professor Hematology, Faculty of Medicine, University Finis Terrae, Av Pedro de Valdivia 1509, Providencia, Santiago, Chile.

出版信息

Case Rep Hematol. 2018 Nov 11;2018:9750532. doi: 10.1155/2018/9750532. eCollection 2018.

Myelodysplasia is a clonal disorder characterized by progressive cytopenias. Intravescial BCG is standard immunotherapy for superficial bladder cancer. We present a patient with transfusion-dependent myelodysplasia whose blood counts normalized during treatment with intravesical BCG for bladder cancer. After finishing treatment, the patient became transfusion dependent once more. We discuss possible mechanisms to explain this case report.