青霉素过敏诊断：一种基于 MOFs 的复合水凝胶用于检测血清中的β-内酰胺酶。
Diagnosis of penicillin allergy: a MOFs-based composite hydrogel for detecting β-lactamase in serum.
机构信息
Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Siping Road 1239, Shanghai 200092, China.
出版信息
Chem Commun (Camb). 2018 Dec 20;55(2):241-244. doi: 10.1039/c8cc08245f.
PMID:30534686
Abstract
An as-synthesized MOFs-based hydrogel exhibits high sensitivity for β-lactamase through an "ON-OFF-OFF-ON" luminescence trigger. It allows achieving an unprecedented strategy for the judgement of penicillin allergy via luminescence detection of β-lactamase in serum.
摘要
一种合成的基于 MOFs 的水凝胶通过“开-关-关-开”的荧光触发对β-内酰胺酶表现出高灵敏度。它通过血清中β-内酰胺酶的荧光检测实现了一种前所未有的青霉素过敏判断策略。
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