抗肿瘤米托蒽醌监测器：基于发光金属有机框架-水凝胶杂化材料的夹心混合基质膜
Antineoplastic Mitoxantrone Monitor: A Sandwiched Mixed Matrix Membrane (MMM) Based on a Luminescent MOF-Hydrogel Hybrid.
作者信息
Lian Xiao, Zhang Yu, Wang Jinmin, Yan Bing
机构信息
Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Siping Road 1239, Shanghai 200092, China.
College of Chemistry and Chemical Engineering, Anhui University, Hefei 230039, China.
出版信息
Inorg Chem. 2020 Jul 20;59(14):10304-10310. doi: 10.1021/acs.inorgchem.0c01451. Epub 2020 Jul 2.
A sandwiched mixed matrix membrane (MMM) based on a metal-organic framework-hydrogel hybrid exhibits eximious performance in the detection of mitoxantrone. Parts per billion-level sensitivity and good selectivity in serum among other analogous antineoplastics have been achieved. This flexible MMM can be used for point-of-care testing drugs in a biological medium.
一种基于金属有机框架-水凝胶杂化材料的夹心混合基质膜（MMM）在检测米托蒽醌方面表现出优异性能。已实现了十亿分之一级的灵敏度以及在血清中相对于其他类似抗肿瘤药物的良好选择性。这种柔性MMM可用于生物介质中即时检测药物。
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