Department of Chemistry, Northern Michigan University, 1401 Presque Isle Ave., Marquette, MI 49855, USA.
Org Biomol Chem. 2018 Dec 19;17(1):172-180. doi: 10.1039/c8ob02249f.
Three generations of Co(iii)-salen complexes containing electron-deficient aromatic moieties (acceptors) have been synthesized. When electron-rich aromatic compounds (donors) were introduced, these complexes were designed to form catalyst assemblies through aromatic donor-acceptor interaction. For all three generations of complexes, the addition of a proper donor led to higher catalytic efficiency in the hydrolytic kinetic resolution (HKR) of epichlorohydrin. The reaction rates are in the following order: Generation 3 > Generation 2 > Generation 1. The aromatic donor-acceptor interaction was verified by NMR spectroscopy and UV-vis absorption spectroscopy studies. These results demonstrated that aromatic donor-acceptor interaction can be a valuable driving force in the assembly of supramolecular catalysts.
已经合成了三代含有缺电子芳香基团（受体）的 Co(iii)-salen 配合物。当引入富电子芳香化合物（供体）时，这些配合物通过芳香供体-受体相互作用被设计成形成催化剂组装体。对于所有三代配合物，添加适当的供体可提高表氯醇水解动力学拆分（HKR）的催化效率。反应速率按以下顺序排列：第三代>第二代>第一代。通过 NMR 光谱和紫外可见吸收光谱研究证实了芳香供体-受体相互作用。这些结果表明，芳香供体-受体相互作用可以成为超分子催化剂组装的一个有价值的驱动力。
