Department of Internal Medicine, Hirata Central Hospital, Fukushima, Japan.
Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan.
J Clin Endocrinol Metab. 2019 May 1;104(5):1658-1666. doi: 10.1210/jc.2018-02136.
Intake of stable iodine helps prevent childhood thyroid cancer in nuclear emergencies, but there is limited case information.
We identified the intake rate and the factors associated with no intake among children who did not take stable iodine after the Fukushima disaster.
Retrospective observational study.
Data were obtained from thyroid cancer screenings performed from August through November 2017.
Children in Miharu Town, Fukushima, Japan.
No intervention.
We performed multilevel logistic regression analysis at the regional and individual levels. We qualitatively examined the reasons for no intake of stable iodine based on closed- and open-ended questions.
The rate of distribution was 94.9%, but the intake rate was only 63.5%. Intake was lower in those aged 0 to 2 years compared with those aged ≥3 years (OR, 0.21; 95% CI, 0.11 to 0.36). Parents' intake was positively associated with their children's intake (OR, 61.0; 95% CI, 37.9 to 102.9). The variance partition coefficient for regions was 0.021, suggesting that the intake of stable iodine was more likely affected by individual than by regional factors. Closed-ended questions showed that the main reason for avoiding intake was concern about safety. Open-ended questions for other reasons revealed issues related to the distribution method, information about the effects and adverse effects of iodine, and instructions for iodine intake. There were no symptomatic adverse effects claimed to the town.
The distribution and consumption of stable iodine occurred in Miharu Town after the Fukushima disaster. To prepare for future nuclear emergencies, it is important to explain to both children and parents the need for intake of stable iodine, particularly among young children.
摄入稳定性碘有助于预防核紧急情况下儿童甲状腺癌，但病例信息有限。
我们确定了福岛灾难后未服用稳定性碘的儿童中，不服用碘的摄入率及其相关因素。
回顾性观察性研究。
日本福岛县三春镇。
来自日本福岛县三春镇的儿童。
无干预。
我们在区域和个体层面进行了多层次逻辑回归分析。我们根据封闭式和开放式问题定性地检查了不服用稳定性碘的原因。
分布率为 94.9%，但摄入量仅为 63.5%。0 至 2 岁儿童的摄入量低于≥3 岁儿童（OR，0.21；95%CI，0.11 至 0.36）。父母的摄入量与子女的摄入量呈正相关（OR，61.0；95%CI，37.9 至 102.9）。区域的方差分量系数为 0.021，表明稳定性碘的摄入更可能受个体因素而非区域因素的影响。封闭式问题表明，避免摄入的主要原因是对安全性的担忧。关于其他原因的开放式问题揭示了与分配方法、碘的效果和副作用信息以及碘摄入说明有关的问题。没有向该镇报告任何有症状的不良影响。
在福岛灾难后，三春镇分发和消费了稳定性碘。为了为未来的核紧急情况做准备，向儿童及其父母解释摄入稳定性碘的必要性非常重要，特别是对幼儿而言。
