Tommasino F, Rovituso M, Lorentini S, La Tessa C, Petringa G, Cirrone P, Romano F, Scifoni E, Schwarz M, Durante M
Department of Physics, University of Trento, Povo, Italy.
Trento Institute for Fundamental Physics and Applications (TIFPA), National Institute for Nuclear Physics (INFN), Povo, Italy.
Radiat Prot Dosimetry. 2019 May 1;183(1-2):274-279. doi: 10.1093/rpd/ncy238.
The recent worldwide spread of Proton Therapy centers paves the way to new opportunities for basic and applied research related to the use of accelerated proton beams. Clinical centers make use of proton beam energies up to about 230 MeV. This represents an interesting energy range for a large spectrum of applications, including detector testing, radiation shielding and space research. Additionally, radiobiology research might benefit for a larger availability of proton beams, especially in those centers where a room dedicated to research activities also exists. Here, we describe the initial activities for the setup of a radiobiology irradiation facility at the Trento Proton Therapy Center. Data referring to the characterization of the beam in air are essential to that purpose and will be presented. A basic setup for large field irradiation will be also proposed, which is needed for the majority of in vitro and in vivo radiobiology experiments.
近期质子治疗中心在全球范围内的扩张为与加速质子束应用相关的基础研究和应用研究带来了新机遇。临床中心使用的质子束能量高达约230兆电子伏特。这对于包括探测器测试、辐射屏蔽和空间研究在内的众多应用而言，是一个很有意思的能量范围。此外，放射生物学研究可能会因质子束的更多可获取性而受益，尤其是在那些设有专门用于研究活动房间的中心。在此，我们描述了在特伦托质子治疗中心建立放射生物学辐照设施的初步活动。为此目的，有关空气中束流特性的数据至关重要，将予以呈现。还将提出一种用于大野照射的基本设置，这是大多数体外和体内放射生物学实验所必需的。
