Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, South Korea.
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Adv Mater. 2019 Feb;31(5):e1805092. doi: 10.1002/adma.201805092. Epub 2018 Dec 7.
Antibiotic-resistant bacteria have emerged as a severe threat to human health. As effective antibacterial therapies, supramolecular materials display unprecedented advantages because of the flexible and tunable nature of their noncovalent interactions with biomolecules and the ability to incorporate various active agents in their platforms. Herein, supramolecular antibacterial materials are discussed using a format that focuses on their fundamental active elements and on recent advances including material selection, fabrication methods, structural characterization, and activity performance.
抗生素耐药菌的出现对人类健康构成了严重威胁。超分子材料作为有效的抗菌治疗方法,由于其与生物分子的非共价相互作用具有灵活可调的性质,并且能够在其平台中纳入各种活性药物,因此具有前所未有的优势。本文以超分子抗菌材料的基本活性元素为重点,并结合近年来的研究进展,包括材料选择、制备方法、结构表征和活性性能等方面,对超分子抗菌材料进行了讨论。