Suppr超能文献

头颈癌幸存者吞咽困难及相关结果的两年患病率:一项更新的监测、流行病学和最终结果(SEER)-医疗保险分析

Two-year prevalence of dysphagia and related outcomes in head and neck cancer survivors: An updated SEER-Medicare analysis.

作者信息

Hutcheson Katherine A, Nurgalieva Zhannat, Zhao Hui, Gunn Gary B, Giordano Sharon H, Bhayani Mihir K, Lewin Jan S, Lewis Carol M

机构信息

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.

出版信息

Head Neck. 2019 Feb;41(2):479-487. doi: 10.1002/hed.25412. Epub 2018 Dec 7.

Abstract

BACKGROUND

The aim of the study was to examine prevalence of dysphagia at the population level in head and neck cancer (HNC) survivors.

METHODS

Surveillance, Epidemiology, and End Results-Medicare claims among 16 194 patients with HNC (2002-2011) were analyzed to estimate 2-year prevalence of dysphagia, stricture, and aspiration pneumonia, and derive treatment- and site-specific estimates.

RESULTS

Prevalence of dysphagia, stricture, pneumonia, and aspiration pneumonia was 45.3% (95% confidence interval [CI]: 44.5-46.1), 10.2% (95% CI: 9.7-10.7), 26.3% (95% CI: 25.6-26.9), and 8.6% (95% CI: 8.2-9.1), respectively. Dysphagia increased by 11.7% over the 10-year period (P < .001). Prevalence was highest after chemoradiation and multimodality therapy.

CONCLUSION

Comparing to published rates using similar methodology the preceding decade (1992-1999), prevalence of dysphagia based on claims data was similar in 2002-2011 in this study. These results suggest persistence of dysphagia as a highly prevalent morbidity, even in the decade in which highly conformal radiotherapy and minimally invasive surgeries were popularized.

摘要

背景

本研究旨在调查头颈癌(HNC)幸存者群体中吞咽困难的患病率。

方法

分析了16194例HNC患者(2002 - 2011年)的监测、流行病学和最终结果 - 医疗保险索赔数据,以估计吞咽困难、狭窄和吸入性肺炎的2年患病率,并得出治疗和部位特异性估计值。

结果

吞咽困难、狭窄、肺炎和吸入性肺炎的患病率分别为45.3%(95%置信区间[CI]:44.5 - 46.1)、10.2%(95%CI:9.7 - 10.7)、26.3%(95%CI:25.6 - 26.9)和8.6%(95%CI:8.2 - 9.1)。在这10年期间,吞咽困难患病率增加了11.7%(P < 0.001)。放化疗和多模式治疗后的患病率最高。

结论

与前十年(1992 - 1999年)使用类似方法公布的患病率相比,本研究中2002 - 2011年基于索赔数据的吞咽困难患病率相似。这些结果表明,即使在高剂量适形放疗和微创手术普及的十年中,吞咽困难作为一种高度普遍的发病率仍然持续存在。

相似文献

4
Rates of Dysphagia-Related Diagnoses in Long-Term Survivors of Head and Neck Cancers.头颈部癌症长期幸存者的吞咽困难相关诊断率。
Otolaryngol Head Neck Surg. 2019 Oct;161(4):643-651. doi: 10.1177/0194599819850154. Epub 2019 Jun 11.
8
Short- and long-term outcomes of oropharyngeal cancer care in the elderly.老年口咽癌治疗的短期和长期结果
Laryngoscope. 2018 Sep;128(9):2084-2093. doi: 10.1002/lary.27153. Epub 2018 Mar 24.

引用本文的文献

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验