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Obesity-induced CYP2E1 activity in children.

作者信息

Gade Christina, Dalhoff Kim, Petersen Tonny, Riis Troels, Schmeltz Camilla, Chabanova Elizaveta, Christensen Hanne Rolighed, Mikus Gerd, Burhenne Juergen, Holm Jens Christian, Holst Helle

机构信息

Department of Clinical Pharmacology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark.

The Children's Obesity Clinic, Department of Paediatrics, Copenhagen University Hospital Holbaek, Denmark.

出版信息

Br J Clin Pharmacol. 2019 Feb;85(2):458-459. doi: 10.1111/bcp.13813. Epub 2018 Dec 9.

Abstract
摘要

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本文引用的文献

1
CYP2E1 activity and children with obesity: possible confounding factors.
Br J Clin Pharmacol. 2019 Feb;85(2):457. doi: 10.1111/bcp.13769. Epub 2018 Oct 17.
2
Higher chlorzoxazone clearance in obese children compared with nonobese peers.
Br J Clin Pharmacol. 2018 Aug;84(8):1738-1747. doi: 10.1111/bcp.13602. Epub 2018 Jun 3.
3
The CYTONOX trial.
Dan Med J. 2016 May;63(5).
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Robustness of chlorzoxazone as an in vivo measure of cytochrome P450 2E1 activity.
Br J Clin Pharmacol. 2004 Aug;58(2):190-200. doi: 10.1111/j.1365-2125.2004.02132.x.
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Cytochrome P-450 2E1 activity and oxidative stress in alcoholic patients.
Alcohol Alcohol. 2000 Jan;35(1):98-103. doi: 10.1093/alcalc/35.1.98.
7
Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans.
Pharmacogenetics. 1999 Jun;9(3):377-88. doi: 10.1097/00008571-199906000-00013.
8
Chlorzoxazone pharmacokinetics as a marker of hepatic cytochrome P4502E1 in humans.
Am J Gastroenterol. 1998 Nov;93(11):2154-61. doi: 10.1111/j.1572-0241.1998.00612.x.
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Cytochrome P-4502E1: its physiological and pathological role.
Physiol Rev. 1997 Apr;77(2):517-44. doi: 10.1152/physrev.1997.77.2.517.
10

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