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将 CONNECT 框架应用于精准健康和健康差异。

Application of the ConNECT Framework to Precision Health and Health Disparities.

机构信息

Usha Menon, PhD, RN, FAAN, is Professor and Vice Dean of Research, University of South Florida College of Nursing, Tampa, Florida. Kimlin Ashing, PhD, is Founding Director, Center of Community Alliance for Research Education, and Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, California. Mei Wei Chang, PhD, RN, is Associate Professor, The Ohio State University, College of Nursing, Columbus. Shannon M. Christy, PhD, is Assistant Member, Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. Katarina Friberg-Felsted, PhD, is Assistant Professor, College of Nursing, University of Utah Salt Lake City. Virginia Gil Rivas, PhD, is Professor, Department of Psychological Science, University of North Carolina at Charlotte. Clement K. Gwede, PhD, MPH, RN, FAAN, is Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. Qian Lu, MD, PhD, is Associate Professor, Department of Health Disparities Research, MD Anderson Cancer Center, Houston, Texas. Cathy D. Meade, PhD, RN, FAAN, is Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center, and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, Florida. Jamila Sly, PhD, is Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Monica Wang, ScD, MS, is Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health, and Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Betina Yanez, PhD, is Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Karen Yeary, PhD, is Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock. Jean C. Yi, PhD, is Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Kassandra I. Alcaraz, PhD, MPH, is Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, Georgia.

出版信息

Nurs Res. 2019 Mar-Apr;68(2):99-109. doi: 10.1097/NNR.0000000000000329.

DOI:10.1097/NNR.0000000000000329
PMID:30540700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6863736/
Abstract

BACKGROUND

An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.

OBJECTIVES

The aim if this study was to apply the transdisciplinary ConNECT Framework: A Model for Advancing Behavioral Medicine Science and Practice to Foster Health Equity to PH by integrating a population health agenda for reducing health disparities.

METHODS

There are five ConNECT principles: (a) integrating context; (b) fostering a norm of inclusion; (c) ensuring equitable diffusion of innovations; (d) harnessing communication technology; and (e) prioritizing specialized training as an organizing framework to PH, including examples of how to integrate behavioral and socioecological determinants to better understand the contexts of individuals, systems, and place to design targeted treatments and interventions.

RESULTS

We describe proactive, actionable strategies for the systematic application of ConNECT Framework principles to address health equity via the PH initiative. Context and implications for nursing research and practice are also described.

DISCUSSION

The ConNECT Framework emphasizes that diversity inclusion is imperative for true population health benefit from PH, broadly in public health, behavioral medicine, medicine, and nursing, to equip health researchers and practitioners to account for contextual socioecologic data that can be aligned with biologic data for more population responsive and individually tailored interventions to prevent, diagnose, and treat diseases.

摘要

背景

精准健康(PH)的重视促使精准医学研究侧重于生物、行为和环境因素与疾病风险、治疗、预后和影响健康差异的结果之间的相互作用。同样重要的是,改善服务不足人群的健康公平仍然是 PH 努力和目标的核心。

目的

本研究旨在将跨学科 CONNECT 框架:推进行为医学科学和实践的模型以促进健康公平应用于 PH,将减少健康差异的人口健康议程纳入其中。

方法

有五个 CONNECT 原则:(a)整合背景;(b)培养包容的规范;(c)确保创新的公平传播;(d)利用通信技术;(e)优先进行专门培训,作为 PH 的组织框架,包括如何整合行为和社会生态决定因素,以更好地了解个人、系统和环境的背景,从而设计有针对性的治疗和干预措施。

结果

我们描述了通过 PH 计划主动、可操作的策略,以系统地应用 CONNECT 框架原则来解决健康公平问题。还描述了背景和对护理研究和实践的影响。

讨论

CONNECT 框架强调,多样性包容对于从 PH 中真正获得人口健康益处至关重要,在公共卫生、行为医学、医学和护理中广泛应用,使健康研究人员和从业人员能够考虑到与生物数据相匹配的社会生态背景数据,以便为预防、诊断和治疗疾病提供更具人口响应性和个性化的干预措施。