Kuan A K, Jackson F I, Hanson J
University of Alberta, Edmonton, Canada.
J R Soc Med. 1988 Oct;81(10):579-82. doi: 10.1177/014107688808101009.
A retrospective evaluation of radionuclide liver and spleen scintigraphy (LS), ultrasonography (US), and computed tomography (CT) was performed in 88 patients who had pathologically proven cutaneous melanoma. In patients who had all three examinations (n = 24), the matrix analysis showed that CT was significantly more sensitive (0.94) in detecting intra-abdominal metastasis when compared to US (0.62, P less than 0.05) and LS (0.38, P less than 0.01). Sixty-four patients had only US and LS studies. In this group of patients US was found to be more sensitive than LS, 0.88 and 0.54 respectively (P less than 0.01). Furthermore, when CT was compared with US, CT was shown to detect metastases significantly earlier than US (P = 0.03). Overall, CT provided the most accurate means for detecting the intra-abdominal metastases of cutaneous melanoma.
对88例经病理证实为皮肤黑色素瘤的患者进行了放射性核素肝脾闪烁扫描（LS）、超声检查（US）和计算机断层扫描（CT）的回顾性评估。在接受了所有三项检查的患者（n = 24）中，矩阵分析显示，与US（0.62，P < 0.05）和LS（0.38，P < 0.01）相比，CT在检测腹腔内转移方面的敏感性显著更高（0.94）。64例患者仅进行了US和LS检查。在这组患者中，发现US比LS更敏感，分别为0.88和0.54（P < 0.01）。此外，当将CT与US进行比较时，CT显示比US能更早地检测到转移（P = 0.03）。总体而言，CT为检测皮肤黑色素瘤的腹腔内转移提供了最准确的方法。
