Fu Q, Wang G H, Wang Q, Zhu J Q
Changzhou Center for Disease Control and Prevention, Changzhou 213022, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 Oct 20;36(10):759-761. doi: 10.3760/cma.j.issn.1001-9391.2018.10.010.
To investigate the chromosomal aberration rate, micronucleus cell rate and the related factors of radiation workers in Changzhou, provide evidence for the occupational health and safety of radiation workers. Descriptive analysis of the chromosomal aberration rate, micronucleus cell rate and the related factors of 3021 radiation workers who conducted occupational health examination in the Changzhou Center for Disease Control and prevention in 2017, multivariate logistic regression was used to analyze the data. The abnormal rate of chromosome aberration and micronucleus cells of 3021radiation workers in Changzhou were 1.32% and 3.34% respectively. The results of multivariate logistic regression showed that the exposure year (=1.501, 95%:1.0782.089, =0.016) was a risk factor for chromosome aberration. The risk of chromosome aberration in radiation therapy (=6.417, 95%:1.36030.280, =0.019) and interventional radiology (=4.598, 95%:1.68812.524, =0.003) was higher than that of industrial application. the exposure year (=1.245, 95%:1.0071.539, =0.043) is also a risk factor for micronucleus cell rate. The micronucleus cell rate abnormality Risk of nuclear medicine (=3.934, 95%:1.30511.858, =0.015) , radiation therapy (=3.802, 95%:1.10113.128, =0.035) , and interventional radiology (=2.953, 95%:1.324~6.584, =0.008) is higher than industrial application. The chromosome aberration rate and micronucleus rate of workers who are exposed to low dose ionizing radiation for long time are related to the exposure year of radiation workers and the occupational categories involved.
为调查常州市放射工作人员的染色体畸变率、微核细胞率及其相关因素,为放射工作人员的职业健康与安全提供依据。对2017年在常州市疾病预防控制中心进行职业健康检查的3021名放射工作人员的染色体畸变率、微核细胞率及其相关因素进行描述性分析,采用多因素logistic回归进行数据分析。常州市3021名放射工作人员的染色体畸变和微核细胞异常率分别为1.32%和3.34%。多因素logistic回归结果显示,暴露年限(β=1.501,95%CI:1.0782.089,P=0.016)是染色体畸变的危险因素。放射治疗(β=6.417,95%CI:1.36030.280,P=0.019)和介入放射学(β=4.598,95%CI:1.68812.524,P=0.003)中染色体畸变的风险高于工业应用。暴露年限(β=1.245,95%CI:1.0071.539,P=0.043)也是微核细胞率的危险因素。核医学(β=3.934,95%CI:1.30511.858,P=0.015)、放射治疗(β=3.802,95%CI:1.10113.128,P=0.035)和介入放射学(β=2.953,95%CI:1.324~6.584,P=0.008)中微核细胞率异常的风险高于工业应用。长期暴露于低剂量电离辐射的工作人员的染色体畸变率和微核率与放射工作人员的暴露年限和所涉及的职业类别有关。