Yorozuya Wakako, Takahashi Atsushi, Takayanagi Akio, Okabe Ko, Takagi Yoshio
Hakodate Goryokaku Hospital.
Hinyokika Kiyo. 2018 Oct;64(10):415-418. doi: 10.14989/ActaUrolJap_64_10_415.
A 60-year-old man presented at our hospital with gross hematuria. He had been treated for nephrotic syndrome with cyclophosphamide and steroids since he was in his 20s. We detected diffuse hemorrhagic cystitis on cystoscopy and diagnosed him with cyclophosphamide-induced hemorrhagic cystitis. He was hospitalized due to clot retention. We treated him with blood transfusion for severe anemia and conducted continuous bladder irrigation. We performed hyperbaric oxygen therapy and transurethral electric coagulation, and increased the steroid dose. However, we could not control the hematuria. Finally, we performed cystectomy, and he is now well without hematuria. Although cystectomy is the final option, it is important to decide it in a timely manner because a delay decreases the quality of life.
一名60岁男性因肉眼血尿前来我院就诊。他从20多岁起就接受环磷酰胺和类固醇治疗肾病综合征。膀胱镜检查时我们发现弥漫性出血性膀胱炎，并诊断为环磷酰胺诱导的出血性膀胱炎。他因血块潴留住院。我们对他进行输血治疗严重贫血，并进行持续膀胱冲洗。我们进行了高压氧治疗和经尿道电凝，并增加了类固醇剂量。然而，我们无法控制血尿。最后，我们进行了膀胱切除术，他现在情况良好，没有血尿。虽然膀胱切除术是最后的选择，但及时做出决定很重要，因为拖延会降低生活质量。
