Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
Department of Radiation Oncology, University of Duisburg-Essen, Essen, Germany.
Head Neck. 2019 Jan;41(1):170-176. doi: 10.1002/hed.25485. Epub 2018 Dec 13.
To evaluate and compare the diagnostic potential of F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( FDG-PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC).
A total of 32 dedicated head and neck F-FDG PET/MRI datasets were included in this analysis. MRI and F-FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases.
Lesion-based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for F-FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of F-FDG PET/MRI compared to MRI (P < .005).
F-FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, F-FDG PET/MRI outperforms MRI.
评估并比较氟代脱氧葡萄糖正电子发射断层扫描/磁共振成像（FDG-PET/MRI）与 MRI 在前瞻性治疗后对头颈腺样囊性癌（ACC）患者复发诊断中的应用价值。
本研究共纳入 32 例头颈部专用 F-FDG PET/MRI 数据集。由两位阅片者分别在单独的阅片时段内对 MRI 和 FDG-PET/MRI 数据集进行分析，以评估肿瘤复发或转移情况。
基于病灶的灵敏度、特异性、阳性预测值、阴性预测值和诊断准确率分别为 FDG-PET/MRI 组 96%、84%、90%、93%和 91%，MRI 组 77%、94%、95%、73%和 84%，提示 FDG-PET/MRI 的诊断准确率显著高于 MRI（P<0.005）。
FDG-PET/MRI 较 MRI 更有助于检测头颈部 ACC 患者的局部复发和远处转移。特别是在阴性预测值方面，FDG-PET/MRI 优于 MRI。
