18F-FDG PET/MRI 与 MRI 在复发性腺样囊性癌患者中的比较。
F-FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma.
机构信息
Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
Department of Radiation Oncology, University of Duisburg-Essen, Essen, Germany.
出版信息
Head Neck. 2019 Jan;41(1):170-176. doi: 10.1002/hed.25485. Epub 2018 Dec 13.
OBJECTIVES
To evaluate and compare the diagnostic potential of F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( FDG-PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC).
METHODS
A total of 32 dedicated head and neck F-FDG PET/MRI datasets were included in this analysis. MRI and F-FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases.
RESULTS
Lesion-based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for F-FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of F-FDG PET/MRI compared to MRI (P < .005).
CONCLUSION
F-FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, F-FDG PET/MRI outperforms MRI.
目的
评估并比较氟代脱氧葡萄糖正电子发射断层扫描/磁共振成像（FDG-PET/MRI）与 MRI 在前瞻性治疗后对头颈腺样囊性癌（ACC）患者复发诊断中的应用价值。
方法
本研究共纳入 32 例头颈部专用 F-FDG PET/MRI 数据集。由两位阅片者分别在单独的阅片时段内对 MRI 和 FDG-PET/MRI 数据集进行分析，以评估肿瘤复发或转移情况。
结果
基于病灶的灵敏度、特异性、阳性预测值、阴性预测值和诊断准确率分别为 FDG-PET/MRI 组 96%、84%、90%、93%和 91%，MRI 组 77%、94%、95%、73%和 84%，提示 FDG-PET/MRI 的诊断准确率显著高于 MRI（P<0.005）。
结论
FDG-PET/MRI 较 MRI 更有助于检测头颈部 ACC 患者的局部复发和远处转移。特别是在阴性预测值方面，FDG-PET/MRI 优于 MRI。
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