经胆固醇糖苷刺激的固有自然杀伤 T 细胞可调节过敏和迟发型超敏反应中的免疫应答。

Invariant natural killer T cells stimulated with cholesteryl glycosides modulate immune responses in allergy and delayed-type hypersensitivity.

机构信息

Tsukuba Research Center for Interdisciplinary Materials Science and Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Department of Health and Dietetics, Faculty of Health and Medical Science, Teikyo Heisei University.

出版信息

Eur J Immunol. 2019 Feb;49(2):348-350. doi: 10.1002/eji.201847825. Epub 2019 Jan 4.

DOI:10.1002/eji.201847825

PMID:30549010

Abstract

Invariant NKT cells were stimulated with cholesteryl O-acyl α-glycosides in the context of CD1d. The activated NKT cells have potential to sustain the homeostasis in the body exposed to excess in either Th1- or Th2-immunity.

摘要

在 CD1d 的背景下，不变自然杀伤 T 细胞被胆固醇 O-酰基 α-糖苷激活。激活的不变自然杀伤 T 细胞有可能维持暴露于过多 Th1 或 Th2 免疫中的体内内环境稳定。