Department of Medicine (Austin Health), University of Melbourne, Heidelberg Heights, Victoria, Australia.
Royal Women's Hospital, Parkville, Victoria, Australia.
Obes Rev. 2019 Apr;20(4):510-526. doi: 10.1111/obr.12804. Epub 2018 Dec 13.
The prevalence of women of child-bearing age with obesity continues to rise at an alarming rate. This has significant implications for both the short-term and long-term health of mother and offspring. Given the paucity of evidence-based literature in this field, the preconception management of women with obesity is highly variable both between institutions and around the world. This systematic review aims to evaluate studies that inform us about the role of preconception weight loss in the fertility and pregnancy outcomes of women with obesity. Current therapeutic interventions are discussed, with a specific focus on the suitability of weight loss interventions for women with obesity planning pregnancy. There are significant knowledge gaps in the current literature; these are discussed and areas for future research are explored.
处于生育年龄段的肥胖女性的患病率持续以惊人的速度上升。这对母婴的短期和长期健康都有重大影响。鉴于该领域缺乏基于证据的文献，肥胖女性的孕前管理在机构之间和世界各地差异很大。本系统评价旨在评估告知我们关于肥胖女性孕前减肥对其生育和妊娠结局的作用的研究。目前讨论了治疗干预措施，特别关注适合计划怀孕的肥胖女性的减肥干预措施。当前文献中存在重大知识空白；这些问题进行了讨论，并探讨了未来研究的领域。
