Cusmano F, Piazza P, De Donatis M, Montanari E, Saginario A, Bassi P
Istituto di Radiologia, Cattedra di Neuroradiologia, Università, Parma.
Radiol Med. 1988 Oct;76(4):262-73.
The clinical and angiographic features of 20 patients affected by internal carotid artery dissection are reported. In one patient the neurological signs were related to a traumatic event, in two cases the symptoms presented after hyperextension of the neck during athletic events, while their onset was apparently spontaneous in the remaining 17 patients. Plain CT was normal in 14 cases and positive for ischemic necrosis in 6 patients. Angiography demonstrated extensive/segmental stenosis of the internal carotid lumen in 12 cases (60%), pseudoaneurysmal dilatation in 3 cases (15%), and complete carotid occlusion in 5 patients (25%). The "double lumen" feature was seen in 3 cases at the origin of the dissection. One patient died, surgical ligature of the internal carotid artery was performed in two cases, while the other patients received medical treatment with platelet inhibitors, except for the young patient affected by post-traumatic artery dissection. Complete recovery was observed in 82% of the patients. Follow-up angiograms demonstrated normal recanalization of the internal carotid artery in 4 out of 6 patients; one of them had two false aneurysms which following angiograms demonstrated to be completely resolved. Regression of stenosis was observed in 6 of the remaining patients by Doppler US. On the whole, the recanalization of the internal carotid artery was observed in 59% of cases. Angiographic findings seemed not to play a decisive role in the prognosis of carotid dissections, which largely depends on the overall patient's condition and on the presence/absence of ischemic cerebral damages.
报告了20例颈内动脉夹层患者的临床和血管造影特征。1例患者的神经症状与创伤事件有关,2例患者在体育活动中颈部过度伸展后出现症状,其余17例患者症状发作明显为自发。14例患者的平扫CT正常,6例患者显示缺血性坏死阳性。血管造影显示12例(60%)颈内动脉管腔广泛/节段性狭窄,3例(15%)假性动脉瘤样扩张,5例(25%)颈内动脉完全闭塞。3例在夹层起始处可见“双腔”特征。1例患者死亡,2例患者行颈内动脉手术结扎,其余患者除受创伤性动脉夹层影响的年轻患者外,均接受血小板抑制剂药物治疗。82%的患者实现完全康复。随访血管造影显示,6例患者中有4例颈内动脉正常再通;其中1例有2个假性动脉瘤,后续血管造影显示完全消失。其余患者中有6例通过多普勒超声观察到狭窄程度减轻。总体而言,59%的病例观察到颈内动脉再通。血管造影结果似乎对颈动脉夹层的预后不起决定性作用,其预后很大程度上取决于患者的整体状况以及是否存在缺血性脑损伤。