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Constipation in a cohort prospective in adult critically ill patients: How much occurs and why?

作者信息

Batassini É, Beghetto M G

机构信息

Postgraduate Program in Nursing, Nursing School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil; Intensive Care Unit, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brasil.

Postgraduate Program in Nursing, Nursing School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil.

出版信息

Enferm Intensiva (Engl Ed). 2019 Jul-Sep;30(3):127-134. doi: 10.1016/j.enfi.2018.05.001. Epub 2018 Dec 12.

DOI:10.1016/j.enfi.2018.05.001
PMID:30553741
Abstract

OBJECTIVE

To assess the incidence and factors associated with constipation in adult critical care patients.

DESIGN

Prospective cohort study.

SETTING

Intensive care unit (ICU) of a high-complexity hospital from November 2015 to October 2016.

PATIENTS

Adults who were hospitalized for at least 72h in the ICU were followed from their admission to the ICU until their departure.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

In the 157 patients followed up, the incidence of constipation was 75.8%. The univariate analysis showed that constipated patients were younger, used more sedation and showed more respiratory and postoperative causes for hospitalization, while non-constipated patients were hospitalized more for gastrointestinal reasons. The use of vasoactive substances, mechanical ventilation and haemodialysis was similar between the constipated and non-constipated patients. Multivariate analysis, days of use of docusate+bisacodyl (HR: .79; 95% CI: .65-.96) of omeprazole or ranitidine (HR: .80; 95%CI: .73-.88) and lactulose (HR: .87; 95%CI: .76-.99) were independent protection factors for constipation.

CONCLUSION

Constipation has a high incidence among adult critical care patients. Days of drug use acting on the digestive tract (lactulose, docusate+bisacodyl and omeprazole and/or ranitidine) are able to prevent this outcome.

摘要

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