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SMART-CPT 用于患有共病创伤后应激障碍和创伤性脑损伤史的退伍军人:一项随机对照试验。

SMART-CPT for veterans with comorbid post-traumatic stress disorder and history of traumatic brain injury: a randomised controlled trial.

机构信息

Psychology Service, VA San Diego Healthcare System, San Diego, California, USA

Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, California, USA.

出版信息

J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):333-341. doi: 10.1136/jnnp-2018-319315. Epub 2018 Dec 15.

DOI:10.1136/jnnp-2018-319315
PMID:30554135
Abstract

OBJECTIVE

To better concurrently address emotional and neuropsychological symptoms common in veterans with comorbid post-traumatic stress disorder (PTSD) and history of traumatic brain injury (TBI), we integrated components of compensatory cognitive training from the Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) programme into cognitive processing therapy (CPT) for PTSD to create a hybrid treatment, SMART-CPT (CogSMART+CPT). This study compared the efficacy of standard CPT with SMART-CPT for treatment of veterans with comorbid PTSD and history of TBI reporting cognitive symptoms.

METHODS

One hundred veterans with PTSD, a history of mild to moderate TBI and current cognitive complaints were randomised and received individually delivered CPT or SMART-CPT for 12 weeks. Participants underwent psychological, neurobehavioural and neuropsychological assessments at baseline, on completion of treatment and 3 months after treatment.

RESULTS

Both CPT and SMART-CPT resulted in clinically significant reductions in PTSD and postconcussive symptomatology and improvements in quality of life. SMART-CPT resulted in additional improvements in the neuropsychological domains of attention/working memory, verbal learning/memory and novel problem solving.

CONCLUSION

SMART-CPT, a mental health intervention for PTSD, combined with compensatory cognitive training strategies, reduces PTSD and neurobehavioural symptoms and also provides added value by improving cognitive functioning.

摘要

目的

为了更好地同时解决患有共病创伤后应激障碍(PTSD)和创伤性脑损伤(TBI)病史的退伍军人常见的情绪和神经心理症状,我们将认知症状管理和康复治疗(CogSMART)计划中的补偿性认知训练成分整合到 PTSD 的认知加工治疗(CPT)中,创建了一种混合治疗方法,即 SMART-CPT(CogSMART+CPT)。本研究比较了标准 CPT 与 SMART-CPT 治疗报告认知症状的共病 PTSD 和 TBI 病史退伍军人的疗效。

方法

100 名 PTSD 退伍军人、轻度至中度 TBI 病史和当前认知症状的退伍军人被随机分配并接受个体 CPT 或 SMART-CPT 治疗 12 周。参与者在基线、治疗结束时和治疗结束后 3 个月接受心理、神经行为和神经心理学评估。

结果

CPT 和 SMART-CPT 均导致 PTSD 和脑震荡后症状的临床显著减轻,生活质量得到改善。SMART-CPT 还导致注意力/工作记忆、言语学习/记忆和新问题解决等认知领域的额外改善。

结论

SMART-CPT 是一种针对 PTSD 的心理健康干预措施,结合补偿性认知训练策略,可减少 PTSD 和神经行为症状,并通过改善认知功能提供额外价值。

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