Saba Luca, Argioas Giovanni Maria, Lucatelli Pierleone, Lavra Francesco, Suri Jasjit S, Wintermark Max
Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari, Polo di Monserrato s.s. 554 Monserrato, 09045, Cagliari, Italy.
Department of Radiology, AOB di Cagliari, 09045, Cagliari, Italy.
Neuroradiology. 2019 Mar;61(3):285-291. doi: 10.1007/s00234-018-2142-x. Epub 2018 Dec 15.
To investigate the variation in the quantification of the carotid degree of stenosis (DoS) with a dual energy computed tomography (CT), using different energy levels during the image reconstruction.
In this retrospective study, 53 subjects (37 males; mean age 67 ± 11 years; age range 47-83 years) studied with a multi-energy CT scanner were included. Datasets were reconstructed on a dedicated workstation and from the CT raw data multiple datasets were generated at the following monochromatic energy levels: 66, 70, 77, and 86 kilo-electronvolt (keV). Two radiologists independently performed all measurements for quantification of the degree of stenosis. Wilcoxon test was used to test the differences between the Hounsifield unit (HU) values in the plaques at different keV.
The Wilcoxon analysis showed a statistically significant difference (p = 0.001) in the DoS assessment among the different keVs selected. The Bland-Altman analysis showed that the DoS difference had a linear relation with the keV difference (the bigger is the difference in keV, the bigger is the variation in DoS) and that for different keVs, the difference in DoS is reduced with its increase.
A standardization in the use of the energy level during the image reconstruction should be considered.
利用双能计算机断层扫描（CT），通过在图像重建过程中使用不同能量水平，研究颈动脉狭窄程度（DoS）量化的变化。
在这项回顾性研究中，纳入了53名使用多能CT扫描仪进行研究的受试者（37名男性；平均年龄67±11岁；年龄范围47 - 83岁）。数据集在专用工作站上重建，并从CT原始数据中生成以下单色能量水平的多个数据集：66、70、77和86千电子伏特（keV）。两名放射科医生独立进行所有狭窄程度量化测量。采用Wilcoxon检验来测试不同keV下斑块中Hounsfield单位（HU）值之间的差异。
Wilcoxon分析显示，在所选择的不同keV之间，DoS评估存在统计学显著差异（p = 0.001）。Bland - Altman分析表明，DoS差异与keV差异呈线性关系（keV差异越大，DoS变化越大），并且对于不同keV，DoS差异随着keV增加而减小。
应考虑在图像重建过程中能量水平使用的标准化。
