Hoy W E, Cestero R V, Freeman R B
Nephron. 1978;20(4):182-8. doi: 10.1159/000181220.
Lymphopenia of a group of uremic patients was associated with normal percentages of T cells but reduced percentages of B cells. Lymphocyte counts improved after a period of maintenance hemodialysis, although not to control levels, and B cell percentages returned towards normal. Uremia is therefore associated with depression of total T and B cell numbers, with a relatively more pronounced effect on B cells. A period of maintenance hemodialysis produces increase in numbers of both cell types and depression becomes nonselective.
一组尿毒症患者存在淋巴细胞减少，其T细胞百分比正常，但B细胞百分比降低。经过一段时间的维持性血液透析后，淋巴细胞计数有所改善，尽管未恢复到对照水平，且B细胞百分比恢复至正常。因此，尿毒症与T细胞和B细胞总数降低有关，对B细胞的影响相对更明显。一段时间的维持性血液透析会使两种细胞类型的数量增加，且这种降低变得不再具有选择性。
