Benito-Pascual B, Pascual-Prieto J, Martínez-de-la-Casa J M, Sáenz-Francés F, Santos-Bueso E
Servicio de Oftalmología, Hospital Clínico San Carlos, Madrid, Spain.
Servicio de Oftalmología, Hospital Clínico San Carlos, Madrid, Spain.
J Fr Ophtalmol. 2019 Jan;42(1):11-15. doi: 10.1016/j.jfo.2018.05.007. Epub 2018 Dec 13.
To study Haab striae in adults with primary congenital glaucoma and describe them by anterior segment optical coherence tomography, as well as analyze their evolution over the patient's lifetime.
Three patients with primary congenital glaucoma were recruited, aged between 17 and 48 years old, with incidentally noted Haab striae on glaucoma consultation. They were studied by: slit lamp; anterior segment optical coherence tomography, Heidelberg Engineering Inc., Germany, (with anterior segment module) and Cirrus HD-OCT, Carl Zeiss Meditec, Dublin, California, USA (with 3D reconstruction); and specular biomicroscopy. The results obtained were contrasted with other studies performed in children.
Rounded excrescences protruding towards the anterior chamber were found, as well as dense, irregular tissue between them. In addition, endothelial abnormalities (polymegathism and polymorphism) were found. These findings fit the evolution of those obtained in pediatric studies and remain stable in adult life.
Through noninvasive methods such as optical coherence tomography and specular biomicroscopy, it is possible to make the diagnosis and follow up these patients. The findings suggest posterior corneal topographic changes; additional studies on this subject may be necessary.
研究原发性先天性青光眼成人患者的哈布条纹，并通过眼前节光学相干断层扫描对其进行描述，同时分析其在患者一生中的演变情况。
招募了3例原发性先天性青光眼患者，年龄在17至48岁之间，在青光眼会诊时偶然发现有哈布条纹。对他们进行了以下检查：裂隙灯检查；使用德国海德堡工程公司的眼前节光学相干断层扫描（配备眼前节模块）以及美国加利福尼亚州都柏林卡尔蔡司医疗技术公司的Cirrus HD-OCT（进行三维重建）；以及镜面生物显微镜检查。将获得的结果与在儿童中进行的其他研究进行对比。
发现有向前房突出的圆形赘生物，以及它们之间致密、不规则的组织。此外，还发现了内皮异常（大小不均和形态不一）。这些发现与儿科研究中获得的结果演变情况相符，并且在成年期保持稳定。
通过光学相干断层扫描和镜面生物显微镜检查等非侵入性方法，可以对这些患者进行诊断和随访。这些发现提示角膜后表面地形发生了变化；可能需要对此主题进行更多研究。
