Rothschild P, Kimme-Smith C, Bassett L W, Gold R H
Iris Cantor Mammography Screening Clinic, Department of Radiological Sciences, UCLA School of Medicine 90024.
Ultrasound Med Biol. 1988;14 Suppl 1:113-9. doi: 10.1016/0301-5629(88)90054-3.
Of 1757 consecutive women patients examined with ultrasound (US) between 1983-1986, 796 patients were asymptomatic, had no masses on their mammograms, and were scanned with whole breast US because their breasts were radiodense on mammography. Combinations of automated and real-time hand-held equipment, ranging in frequency from 3.9 MHz to 10 MHz. were used. Of the 796 examinations, 71.5%(569) were normal, 23.5%(187) disclosed cysts, and 4.3%(40) revealed solid masses. Four masses were biopsied, yielding one malignancy, two fibroadenomas and one normal breast tissue. All but 4 of the remaining 36 asymptomatic women with solid masses had a follow-up period of at least 1 year. In the authors' opinion, this low yield of one breast cancer in 796 asymptomatic women implies that whole breast US is of little value (in terms of breast cancer detection) in breasts that are radiodense but otherwise negative on mammography.
在1983年至1986年间接受超声（US）检查的1757例连续女性患者中，796例患者无症状，乳房X线照片上没有肿块，且由于其乳房在乳房X线摄影中表现为致密型而接受了全乳超声扫描。使用了频率范围从3.9兆赫到10兆赫的自动和实时手持设备组合。在这796次检查中，71.5%（569例）正常，23.5%（187例）发现囊肿，4.3%（40例）发现实性肿块。对4个肿块进行了活检，结果为1例恶性肿瘤、2例纤维腺瘤和1例正常乳腺组织。其余36例无症状实性肿块女性中，除4例患者外，其余患者的随访期至少为1年。作者认为，在796例无症状女性中仅发现1例乳腺癌的低检出率意味着，对于乳房X线摄影表现为致密型但其他方面为阴性的乳房，全乳超声（就乳腺癌检测而言）价值不大。
