Jackson V P
Department of Radiology, Indiana University School of Medicine, Indianapolis 46202.
Ultrasound Med Biol. 1988;14 Suppl 1:131-7. doi: 10.1016/0301-5629(88)90056-7.
A commercially available duplex ultrasound unit was used to examine 54 breast lesions in 44 women. The 7.5 MHz imaging probe contained a 3 MHz pulsed Doppler crystal, and the 10 MHz imaging probe contained a 4.5 MHz pulsed Doppler crystal. Doppler signals were elicited from normal breast tissue in only one patient. No Doppler signals were found in the five cysts examined in this study. For the 35 solid masses with biopsy or adequate follow-up that were examined with one or both probes, the sensitivity of Doppler for the diagnosis of carcinoma was 69%, the specificity 59%, positive predictive value 50%, negative predictive value 76%, and the accuracy 63%. Because of intermittent malfunction of the 10/4.5 MHz probe, some patients were examined with only the lower frequency probe. For the 34 solid lesions with biopsy or adequate follow-up that were examined with the 7.5/3 MHz probe, the sensitivity was 62%, specificity 38%, positive predictive value 50%, negative predictive value 72%, and accuracy 62%.
使用一台市售的双功能超声设备对44名女性的54个乳腺病变进行检查。7.5兆赫成像探头包含一个3兆赫脉冲多普勒晶体，10兆赫成像探头包含一个4.5兆赫脉冲多普勒晶体。仅在一名患者的正常乳腺组织中引出了多普勒信号。在本研究中检查的5个囊肿中未发现多普勒信号。对于用一个或两个探头检查的35个有活检或充分随访的实性肿块，多普勒诊断癌的敏感性为69%，特异性为59%，阳性预测值为50%，阴性预测值为76%，准确性为63%。由于10/4.5兆赫探头间歇性故障，一些患者仅用低频探头进行了检查。对于用7.5/3兆赫探头检查的34个有活检或充分随访的实性病变，敏感性为62%，特异性为38%，阳性预测值为50%，阴性预测值为72%，准确性为62%。
