2014-2016 年瑞典宫颈癌筛查情况
Cervical cancer screening in Sweden 2014-2016.
机构信息
Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
出版信息
PLoS One. 2018 Dec 17;13(12):e0209003. doi: 10.1371/journal.pone.0209003. eCollection 2018.
BACKGROUND
To enable incremental optimization of screening, regular reporting of quality indicators is required.
AIM
To report key quality indicators and basic statistics about cervical screening in Sweden.
METHODS
We collected individual level data on all cervical cytologies, histopathologies, human papillomavirus tests and all invitations for cervical screening in Sweden during 2013-2016.
RESULTS
There were over 2,278,000 cervical samples collected in Sweden in 2014-2016. Organized samples (resulting from an invitation) constituted 69% of samples. The screening test coverage of all resident women aged 23-60 was 82%. The coverage has slowly increased for >10 years. There is large variability between counties (from 71% to 92%) over time. There were 25,725 women with high-grade lesions in cytology during 2013-2015. Only 96% of these women had a follow-up histopathology within a year. Cervical cancer incidence showed an increasing trend.
CONCLUSION
Key quality indicators such as population coverage and follow-up rates were stable or improving, but there was nevertheless an unexplained cervical cancer increase.
背景
为了实现筛查的逐步优化，需要定期报告质量指标。
目的
报告瑞典宫颈筛查的关键质量指标和基本统计数据。
方法
我们收集了 2013-2016 年期间瑞典所有宫颈细胞学、组织病理学、人乳头瘤病毒检测和所有宫颈筛查邀请的个体水平数据。
结果
2014-2016 年期间，瑞典共采集了超过 227.8 万份宫颈样本。有组织的样本（来源于邀请）占样本的 69%。所有 23-60 岁常住女性的筛查测试覆盖率为 82%。10 多年来，覆盖率缓慢上升。各郡之间的变化很大（71%-92%）。2013-2015 年期间，细胞学检查中有 25725 名女性患有高级别病变。这些女性中只有 96%在一年内进行了后续组织病理学检查。宫颈癌发病率呈上升趋势。
结论
人群覆盖率和随访率等关键质量指标稳定或有所改善，但宫颈癌仍呈上升趋势，原因不明。
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