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人类暴露组评估平台。

Human exposome assessment platform.

作者信息

Merino Martinez Roxana, Müller Heimo, Negru Stefan, Ormenisan Alex, Arroyo Mühr Laila Sara, Zhang Xinyue, Trier Møller Frederik, Clements Mark S, Kozlakidis Zisis, Pimenoff Ville N, Wilkowski Bartlomiej, Boeckhout Martin, Öhman Hanna, Chong Steven, Holzinger Andreas, Lehtinen Matti, van Veen Evert-Ben, Bała Piotr, Widschwendter Martin, Dowling Jim, Törnroos Juha, Snyder Michael P, Dillner Joakim

机构信息

Karolinska Institutet, Stockholm, Sweden.

Medical University Graz, Graz, Austria.

出版信息

Environ Epidemiol. 2021 Dec 3;5(6):e182. doi: 10.1097/EE9.0000000000000182. eCollection 2021 Dec.

Abstract

The Human Exposome Assessment Platform (HEAP) is a research resource for the integrated and efficient management and analysis of human exposome data. The project will provide the complete workflow for obtaining exposome actionable knowledge from population-based cohorts. HEAP is a state-of-the-science service composed of computational resources from partner institutions, accessed through a software framework that provides the world's fastest Hadoop platform for data warehousing and applied artificial intelligence (AI). The software, will provide a decision support system for researchers and policymakers. All the data managed and processed by HEAP, together with the analysis pipelines, will be available for future research. In addition, the platform enables adding new data and analysis pipelines. HEAP's final product can be deployed in multiple instances to create a network of shareable and reusable knowledge on the impact of exposures on public health.

摘要

人类暴露组评估平台(HEAP)是一个用于综合高效管理和分析人类暴露组数据的研究资源。该项目将提供从基于人群的队列中获取可用于暴露组的可操作知识的完整工作流程。HEAP是一项科学前沿服务,由来自合作机构的计算资源组成,通过一个软件框架进行访问,该框架提供了世界上最快的用于数据仓库和应用人工智能(AI)的Hadoop平台。该软件将为研究人员和政策制定者提供决策支持系统。HEAP管理和处理的所有数据以及分析管道都将可供未来研究使用。此外,该平台还支持添加新数据和分析管道。HEAP的最终产品可以部署在多个实例中,以创建一个关于暴露对公众健康影响的可共享和可重复使用知识的网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4caf/8663864/fc206f78bbb6/ee9-5-e182-g001.jpg

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